Peribiliary region is the anatomical space adjoining  the intra and extrahepatic biliary system and comprises of portal vein, hepatic artery, nerves and  lymphatics. This region is prone to several pathologies ranging from congenital, infective, inflammatory, traumatic and  neoplastic. Due to the wide spectrum of abnormalities,  it is often difficult to reach a final diagnosis. This review focusses to draw a roadmap to help reach a diagnosis of abnormalities encountered in this region by highlighting the characteristic imaging features associated with these abnormalities.